Hallie Sam

The rapidly evolving landscape of international trade policies has created distinct challenges for biotechnology companies, yet smaller firms are discovering unique pathways to success. Leen Kawas, Managing General Partner at Propel Bio Partners, reveals how emerging biotech organizations can leverage their inherent characteristics to thrive amid tariff uncertainties.

Small biotech companies face particular vulnerability in the current environment, with market analysis showing these firms are “particularly vulnerable to tariffs, as they rely on imported APIs” and often maintain leaner inventory levels. The implementation of tariffs ranging from 10% to 25% on imports from key regions has significantly disrupted established supply chains and increased operational costs.

However, Leen Kawas identifies specific advantages that set small biotechs apart. These organizations excel at making rapid decisions and implementing changes without the bureaucratic delays that hinder larger competitors. This agility allows them to adapt mitigation strategies within days rather than requiring months for organizational approval processes.

Research confirms the innovative capacity of smaller biotechs, with studies showing they originated 46% of first-in-class cancer drugs approved between 2010 and 2020, compared to just 14% from larger pharmaceutical companies. This innovative mindset extends beyond drug development to creative supply chain management approaches.

Strategic focus represents another critical advantage. Unlike diversified pharmaceutical corporations that manage impacts across numerous product lines, small biotechs can concentrate their resources on protecting core assets through targeted solutions. As Leen Kawas explains, “This focused approach can be advantageous when navigating supply chain disruptions.”

Technology adoption has emerged as an equalizer. Cloud-based supply chain visibility platforms, once exclusive to larger organizations, now enable small biotechs to model tariff scenarios and anticipate disruptions. These tools provide capabilities for proactive rather than reactive management strategies.

Collaborative networks have gained unprecedented significance. Strategic partnerships with contract research organizations and academic institutions create shared resilience against supply chain shocks. These alliances facilitate resource pooling and enhance negotiating power, which is typically unavailable to individual companies.

Foreign Trade Zones offer tactical advantages, allowing companies to defer, reduce, or eliminate tariffs on imported materials. Many emerging biotech companies now establish operations within these zones to maintain competitive cost structures.

Reshoring initiatives reflect long-term strategic thinking. Leen Kawas notes that companies are increasingly evaluating the benefits of domestic or regional manufacturing against the risks associated with vulnerable global supply chains.

Case studies demonstrate successful adaptation. One biotech company established a regional consortium for equipment sharing, effectively distributing tariff burdens; another developed proprietary supply chain analytics, gaining competitive advantages through its rapid response capabilities.

Investment patterns reflect evolving priorities. According to Leen Kawas, “Sophisticated investors now evaluate biotech companies based on their supply chain resilience and strategies for mitigating tariffs.” Demonstrating robust approaches to managing trade barriers has become essential for attracting capital.

Looking forward, Leen Kawas predicts structural changes in biotech development models. Regional innovation clusters are emerging as small biotech companies develop shared infrastructure while maintaining individual agility. These collaborative ecosystems strengthen collective resilience against future disruptions.

“The current trade environment demands adaptation, but adaptation has always been the defining characteristic of successful biotech innovators,” concludes Leen Kawas. Companies that embrace this principle position themselves not merely to survive, but to redefine industry standards in an era of global change.

How does TDS work?

Tax Deducted at Source (TDS) is a way for the Indian government to receive taxes that makes sure they are paid on time and correctly and with this method, tax is taken out at the source of the income. This means that the person paying taxes takes out a certain portion of the money before sending it to the recipient. This tax is then sent to the government on the person’s account. Pay cheques, interest from banks, professional fees, rent, sales, and bonuses are all types of income that are subject to TDS. The idea behind TDS is to collect tax at the exact point where income is made. This makes it less likely that people will not pay their taxes and makes sure that the government always has money coming in.

Why is TDS important, and who is responsible?

TDS is a very important part of keeping India’s tax system running smoothly. It makes sure that taxes are paid in a responsible way and helps people avoid having to make big payments at the end of the year. By taking out taxes at the source, the government lowers the chance that people won’t pay them and makes it easier to get money.

Employers, banks, businesses and other groups that make payments that are subject to TDS rules must take TDS out of those payments and leave it with the government but following TDS rules incorrectly can result in big fines, such as interest charges for late payments and extra tax obligations.

Conclusion

Every person needs to know what is TDS is because it has a direct effect on their tax responsibilities and financial planning, TDS makes it easier to collect taxes and helps the Indian tax system work well by making sure that deductions and payments are made on time. Taxpayers need to keep track of their TDS payments to check them with Form 26AS and ask for returns if too much tax was taken out.

People and companies can stay in line with TDS rules and laws and minimise their tax obligations by staying up to date on them; for paid workers, making sure their boss correctly deducts TDS and sends Form 16 on time is very important for filing their taxes and in the same way, business owners, freelancers, and experts must make sure they reduce and send TDS on all funds that apply to stay out of trouble with the law.

TDS is an important part of paying taxes, so it helps stop people from not paying their fair share and keeps people financially responsible. When taxpayers understand how TDS works, they can better handle their money, pay less tax, and help make India’s tax system stronger and more clear.

In today’s hypercompetitive business environment, the difference between thriving enterprises and stagnant organizations often comes down to one critical factor: corporate culture. Few executives understand this reality better than Jack Truong, whose three-decade career transforming underperforming businesses has been built on dismantling what he identifies as the greatest detriment to organizational success—siloed workplaces.

“Siloed workplaces may be the biggest detriment to building a culture of success,” Truong explains. “They are inefficient, deter collaboration, and prevent the company from understanding and then responding quickly to market changes and shifts in demand.”

Throughout his tenures at corporate giants including 3M, Electrolux, and James Hardie, Truong has developed a reputation for revitalizing corporate cultures by fostering environments where cross-functional teams collaborate rather than compete. His approach, which he calls “The foreman and Norman,” establishes open communication channels where all team members can voice their opinions before leadership makes final decisions.

“You want to create the environment at the beginning where all people voice their opinions and voice their questions, concerns, and then so that you get everything out,” Truong elaborates. “You’ve got to allow people to have the opportunity to voice their concerns, their opinions. But then at the end of that period, the CEO has to make the final decision.”

This philosophy has been instrumental in Truong’s success, as detailed in BOSS Magazine’s profile on his consensus-building approach. By creating an inclusive environment that values diverse perspectives, Truong ensures that employees feel invested in the company’s vision and strategy.

Truong’s leadership methodology extends beyond simple consensus-building, however. As featured in CEO World, he consistently applies the 80/20 rule to identify and focus on the 20% of factors that drive 80% of a company’s value. This focused approach allows teams to align around clear priorities rather than becoming distracted by less impactful initiatives.

“As a CEO, you have got to make sure that you directly communicate with the leaders of each one of these critical functions and ensure they come together in saying: ‘This is our strategy, and this is how we are connected and how we are going to execute it together,'” Truong emphasizes.

The results of this approach speak for themselves. At James Hardie Industries, Truong’s cultural transformation contributed to a remarkable 370% increase in market capitalization and an 85% rise in net profits within just three years. His insights on business transformation have earned him recognition as one of the Elite Influencers to Watch in 2024.

Truong recently shared additional perspectives on corporate leadership in a podcast with The Street, demonstrating his continued influence on business thinking.

What distinguishes Truong’s approach is his emphasis on empowering employees while maintaining clear leadership. “Above all, it’s crucial to lead by example and empower employees to take ownership, as well as accountability. This will foster a positive company culture,” he notes. “It’s also equally important that leaders make the tough decisions at the right time to ensure the whole is always greater than the sum of the parts.”

As organizations continue to navigate increasingly complex market conditions, Truong’s insights offer valuable guidance for leaders seeking to break down silos and build unified, effective teams. His career demonstrates that when employees buy into a shared vision and understand how their roles connect to broader objectives, the potential for transformative growth becomes limitless.

Artificial intelligence is changing numerous industries, and customer service is no exception. Today, more companies are considering a virtual AI agent to manage front desk operations, and the benefits are real for large and small businesses alike. Traditionally, businesses had to hire real people to attend to every call, and even with the investment, there was always a risk of missing a valuable call. Companies like Signpost are now offering AI receptionists, which have numerous advantages. In this guide, let’s talk in detail about the various aspects. 

How do AI receptionists work? 

Most AI models are based on advanced natural language processing (NLP) and machine learning. Companies are also deploying speech synthesis to ensure the overall response is as human and conversational as possible. AI is being trained on datasets, and an AI receptionist can process the input and analyze the intent and language. Based on the initial information, the agent can then access information from the knowledge base to offer accurate and precise responses. AI receptionists can do a wide range of things, from attending regular customer calls to taking appointments and bookings. If required, the system can automatically direct the user to the relevant customer care agent. 

Benefits of using AI receptionists

The most obvious advantage of using an AI receptionist is ensuring availability. No matter what time a customer calls, they will get a response, even when the real agents are out of the office. The cost of AI receptionists is also significantly lower, and service providers usually charge on a monthly basis. The package depends on whether you have a large call volume or if the calls are usually of a longer duration. With AI, it is also possible to scale your operations efficiently without spending on staffing. 

Are AI receptionists good for small businesses?

While large businesses with bigger call volumes are the first to use AI receptionists, small businesses can enjoy similar benefits. Firstly, smaller companies can benefit from reduced overheads and the extensive work that goes into hiring front desk receptionists. The core team can focus on more critical aspects, and if required, the AI voice agent can always transfer the call to someone who needs more help or is having a serious problem. 

Elevate your customer experience 

Another reason to use an AI receptionist is to improve the quality of the overall services you offer to customers. When someone calls your office, they will get an answer, and the prompt response of the AI receptionist ensures calls never go to voicemail. AI responses are also accurate and aligned, and there are fewer chances of human errors. 

Should you get away with your real front desk receptionists?

Probably that is not the best idea. Instead, consider blending the best of both options. Using an AI receptionist ensures you always have help and don’t have to bother about your staff leaving the desk. On the other hand, real receptionists can continue to handle more complex issues or matters that need human intervention. Today, more companies are choosing the model as it helps keep costs in check without compromising on customer service. 

More business, better competitive edge

Having an AI receptionist shows that your business cares and happy customers will bring more business and recommend the company further. A virtual front desk also gives you a competitive edge, where you can continue to receive calls and capture all leads instead of callers looking for alternatives when calls go unanswered. 

Check online to find top-rated AI receptionists, and before you choose one, always look at features, pricing, and uptime. You want to be sure the service provider allows you to control responses and scripts. 

The United States semiconductor landscape is undergoing a monumental transformation as TSMC Arizona receives a groundbreaking $6.6 billion federal grant, announced by the Department of Commerce in November 2024. This substantial investment, part of the bipartisan CHIPS and Science Act, signals a decisive move to reestablish America’s position as a global leader in advanced chip manufacturing.

The scope of this initiative extends far beyond the initial grant. TSMC Arizona has committed to a remarkable $65 billion investment in northern Phoenix. This commitment represents the most substantial foreign direct investment ever made in a U.S. greenfield project, complemented by an additional $5 billion in federal loans. The project’s economic impact promises to be transformative. Projections indicate the creation of 6,000 permanent positions across the three planned fabrication facilities and more than 20,000 construction jobs during development.

The first facility entered high-volume production in Q4 2024, marking a watershed moment for American technology manufacturing. This achievement will end decades of dependence on overseas production for the most sophisticated semiconductor components. The timing proves crucial, as the United States currently produces only 10% of the world’s semiconductors, dramatically declining from its previous 40% market share.

The three planned facilities will serve distinct technological needs in the semiconductor landscape. The initial plant will harness TSMC’s N4 process technology, primarily serving the smartphone industry’s demands. Following this, a second facility scheduled for 2028 will employ advanced N3 and N2 process technologies, focusing on chip production for data centers that power sophisticated computing applications. The third and most advanced facility, announced with the federal grant, will manufacture A16 chips and implement groundbreaking 2nm technology, pushing the boundaries of semiconductor capabilities by the decade’s conclusion.

The project has already demonstrated promising results, with early production metrics from the first facility surpassing those of TSMC’s Taiwan-based operations. This success has contributed to TSMC’s strong financial performance, with the company reporting a 14.3% sequential revenue increase and achieving a 59% gross margin in Q4 2024.

TSMC Arizona’s commitment extends beyond manufacturing excellence to environmental stewardship, as demonstrated by plans for an on-site industrial water reclamation facility. This initiative aligns with the company’s sustainability goals, targeting a minimum 90% water recycling rate across operations.

The project exemplifies the broader success of the CHIPS for America program, which has distributed over $10 billion across 20 states since its inception in August 2022. With total proposed funding exceeding $36 billion, the program focuses on strengthening American technology infrastructure through research, development, and workforce advancement investments, particularly in emerging fields such as quantum computing and nanotechnology.

TSMC chairman and CEO Dr. C.C. Wei characterizes the project as a testament to collaborative innovation, highlighting the strategic partnerships between the company and its network of customers, suppliers, and partners. Wei has emphasized that TSMC expects 2025 to be another strong growth year, forecasting revenue to increase by close to mid-20% in U.S. dollar terms.

The development timeline reflects steady progress, with significant milestones already achieved. The project has maintained forward momentum following the 2020 announcement and $12 billion commitment. In December 2022, crucial chipmaking equipment was installed, and the second facility was announced. By February 2024, the second fabrication plant reached its structural completion milestone, followed two months later by the announcement of the third facility.

This comprehensive initiative through TSMC Arizona represents more than just industrial expansion; it signifies a strategic realignment of American technological capabilities. As these facilities progress toward full operational status, they will help advance the nation’s position in global semiconductor production while supporting TSMC’s expanding advanced technology portfolio, which now accounts for 74% of wafer revenue.

The project is a testament to the potential of public-private partnerships in rebuilding critical manufacturing capabilities and ensuring America’s technological sovereignty in the decades ahead.

No cenário empresarial brasileiro, a Eucatex se consolida como um exemplo notável de evolução e adaptabilidade no setor industrial. Sob a gestão estratégica de Flavio Maluf, a empresa, que acumula 73 anos de trajetória, tem redefinido os padrões do mercado moveleiro e da construção civil, estabelecendo novos paradigmas de eficiência e responsabilidade ambiental.

A excelência operacional da empresa foi recentemente reconhecida com sua inclusão na respeitada lista Forbes Agro100 de 2023, ocupando a 81ª posição. Este reconhecimento se fundamenta em um crescimento significativo nas receitas, registrando uma média de 20,2% desde 2021, resultado que reforça a eficácia das estratégias implementadas pela atual gestão.

No âmbito da transformação digital, a empresa tem se destacado pela implementação de soluções inovadoras, incluindo um marketplace B2B pioneiro no segmento de pisos. Esta plataforma digital tem alcançado números expressivos, com aproximadamente um milhão de acessos anuais e 65 mil visitas mensais orgânicas, revolucionando a forma como a empresa se relaciona com seus parceiros comerciais.

A gestão de Flavio Maluf tem priorizado a expansão internacional da Eucatex, que hoje atende a 40 países com produtos customizados para diferentes mercados. A adaptabilidade da empresa é evidenciada pela personalização de cerca de 20% de seu portfólio para atender às especificidades de cada região, com destaque para o mercado norte-americano, principal destino das exportações.

O compromisso ambiental da empresa se materializa em uma operação florestal de grande escala, mantendo 50 milhões de árvores em 35 mil hectares, com produção sustentável de 1,8 milhão de metros cúbicos de madeira anualmente. A capacidade de produzir 13 milhões de mudas clonais por ano demonstra o investimento contínuo em tecnologia e pesquisa para garantir a sustentabilidade da produção.

Na área energética, a empresa estabeleceu uma parceria estratégica para participação no maior projeto de energia solar do Brasil, permitindo que suas unidades industriais obtenham 50% de seu consumo energético de fontes renováveis. Esta iniciativa reforça o compromisso da organização com a sustentabilidade em todas as etapas de sua operação.

O engajamento social da Eucatex se manifesta através de programas consistentes de conscientização ambiental e capacitação profissional, desenvolvidos há mais de vinte anos. A empresa mantém um programa ativo de visitas técnicas para instituições educacionais, promovendo a educação ambiental e o compartilhamento de práticas sustentáveis.

A distribuição equilibrada do faturamento entre os setores moveleiro (41%) e de construção (44%) demonstra a diversificação estratégica do negócio. Com seis unidades industriais no Brasil e presença comercial nos Estados Unidos, a empresa mantém uma estrutura operacional que permite atender com eficiência tanto o mercado interno quanto o externo.

O portfólio de produtos reflete uma profunda compreensão das tendências contemporâneas de consumo, com foco em soluções práticas alinhadas ao conceito “do it yourself”. Esta abordagem se materializa em produtos como portas padronizadas, kits de instalação e linhas de tintas desenvolvidas para facilitar a aplicação pelo próprio consumidor.

A empresa se destaca como pioneira na reciclagem de madeira em larga escala na América Latina, demonstrando seu compromisso com a economia circular. Esta iniciativa se soma a outras práticas sustentáveis que integram o DNA da empresa há mais de três décadas, incluindo programas de reflorestamento e gestão responsável de recursos naturais.

A visão de futuro apresentada por Flavio Maluf para o setor moveleiro brasileiro é marcada pelo otimismo e pela identificação de oportunidades significativas de crescimento. O executivo destaca o potencial do país para aumentar sua participação no mercado global de manufaturados, apoiado em vantagens competitivas naturais como condições climáticas favoráveis e abundância de matéria-prima.

A expectativa para o setor é de uma transformação expressiva no perfil das exportações brasileiras, com uma evolução do atual cenário, onde 70% são commodities, para um futuro em que 90% sejam produtos manufaturados. Esta transição representa uma oportunidade única para empresas com o perfil da Eucatex, que já possuem expertise em produtos de alto valor agregado.

O compromisso com práticas ESG, natural à empresa há mais de três décadas, continua orientando as decisões estratégicas e operacionais. Esta abordagem integrada de sustentabilidade, que engloba aspectos ambientais, sociais e de governança, posiciona a Eucatex como referência no setor e demonstra sua capacidade de criar valor de forma responsável e duradoura.

A modernização constante dos processos produtivos, aliada ao investimento em tecnologia e inovação, tem permitido à empresa manter sua posição de liderança no mercado, estabelecendo novos padrões de qualidade e eficiência para o setor industrial brasileiro. Este compromisso com a excelência operacional e a sustentabilidade continua a ser a marca registrada da gestão da Eucatex.